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Here is a list of the interactions among your drugs.
There is a problem with cannabis and alpraxolam (Xanax) and with duloxetine (Cymbalta).
There is also a problem with duloxetine (Cymbalta) and Lisinopril and with duloxetine (Cymbalta) and alprazolam (Xanax).
Not everyone will experience these interactions though so risk hs to be considered along with benefit.