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The dose of Eliquis for atrial fibrillation (regardless of age and weight) is 5 mg twice a day. Please see the authentic reference;
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The non valvular atrial fibrillation means when there is not valve abnormality. If there is valve issue (like mitral valve prolapse or stenosis /narrowing, which is common in old age due to thickening of valve cusps); the dose need to be kept as 5 mg twice a day to prevent stroke.
In the valve issue (which occurs commonly in the old age due to valve narrowing or prolapse); there is an high incidence of blood clot formation; which in turn can lead to stroke. For prevention of it; full doses are required. The dose reduction is not recommended.
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