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all of the SSRI agents including ditalopram can have risks for increasing intraoccular pressure and causing worsening of glaucoma.
if you have glaucoma, you might need to switch to another type of antidepressant.
mitazapine can cause weight gain.
but this study
showed that it didn't worsen diabetes numbers in patients who had diabetes and took mitazapine.
do you have diabetes and glaucoma?
do you need to take an antidepressant?