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There really isn't any way to say how serious this is until you have a diagnosis. That will come with the results of the biopsy and the CT scan. "Abnormal" just means not normal or usual; it isn't a diagnosis of anything. That will be for further testing to determine.
Abnormal mucosa anywhere in the colon, including the ileocecal valve (the valve at the end of the stomach that allows food to pass into the intestine). It can be Crohn's disease, ulcerative colitis, intestinal malabsorption, or even cancer.
I wish there were more to tell you, but there isn't, and won't be until you have the additional testing recommended by your doctor.