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The extra vein usually is not problematic. But with his symptoms and MRI findings, it is likely to be malformation (abnormal formation). Veins in the brain are called as sinus. Malformation of the sinus or arteries (like aneurysm) can cause many manifestations. These can be identified by angiogrpahy or magnetic resonance arteriography (MRA). Minor surgerical procedures can get rid of them and cure them completely.
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I am not sure if his following investigations were done, which may give clue to cause for lack of energy:
1) Complete blood count,
2) Erythrocyte sedimentation rate,
3) Thyroid function tests,
4) Muscle enzymes;
5) Anti-nuclear antibodies (ANA)
6) Adrenal function test
9) Anti-SSA (Ro) or Anti-SSB (La)
10) Coombs test
12) Creatinine kinase
13) Blood culture
14) Urine culture
15) EBV antibodies.
These are likely to point to a diagnosis.
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An high thyroid which became normal may indicate autoimmune thyroiditis. This may explain the lack of energy. This may go in low thyroid in 6-12 months later on and thus serial estimation of thyroid function tests every 3 months are recommended.
Orange color to skin can be due to medications, if he is taking any. Issues related to liver disorder, also cause it. Liver function tests like SGOT, SGPT etc would be advised.
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