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I am Dr. Arun and will be helping you today.
I am sorry that your question was unanswered for long.
An open wound (termed ulcer which is breech in skin) for 2 years is likely to be / possibilities of diagnosis;
1) A venous ulcer
2) An arterial ulcer (peripheral arterial disease / PAD)
3) Diabetc ulcer / diabetic dermapathy
4) Chronic infection.
5) Chronic osteomyelitis
A biopsy is usually, the diagnostic for it. There are other investigations like (to ascertain the diagnosis);
a) Colored Doppler study
b) Culture test.
Some of these investigations had been already done for you.
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