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Chris C.
Chris C., Nurse
Category: Health
Satisfied Customers: 1078
Experience:  Nurse with with 10+ yrs. in wellness care, geriatrics, hospice and acute care.
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what causes histoplasma yeast values to be 1:8, but histoplasmosis

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what causes histoplasma yeast values to be 1:8, but histoplasmosis myecial values to be negative

Chris C. :

Titer is considered positive at reciprocal dilutions greater than 1:8. A titer with dilutions greater than 1:32 suggests active histoplasmosis infection.

Chris C. :

Yeast phase is regarded as more sensitive. Approximately 90-95 percent of cases have positive titers to one or both antigens. Titers to mycelial antigen are higher in chronic infection. Cross-reactions, usually at lower titers, may occur with other fungal disease. Rising titers suggest progression of infection. Skin tests in individuals previously exposed may cause titer elevation in 17-20 percent of cases.

Chris C. :

Negative fungal serology does not rule out the possibility of current infection.

Customer: So I should be worried about having histoplasmosis then
Chris C. :

You results are borderline positive at best. You do not show a certain positive result that would indicate histoplasmosis. This should be retested at a later date to verify the initial result and then go from there.


Chris C. :

Titer is considered positive at reciprocal dilutions greater than 1:8. A titer with dilutions greater than 1:32 suggests active histoplasmosis infection.

Chris C. :

Yeast phase is regarded as more sensitive. Approximately 90-95 percent of cases have positive titers to one or both antigens. Titers to mycelial antigen are higher in chronic infection. Cross-reactions, usually at lower titers, may occur with other fungal disease. Rising titers suggest progression of infection. Skin tests in individuals previously exposed may cause titer elevation in 17-20 percent of cases.

Chris C. :

Negative fungal serology does not rule out the possibility of current infection.</pCustomer: So I should be worried about having histoplasmosis thenChris C. :

You results are borderline positive at best. You do not show a certain positive result that would indicate histoplasmosis. This should be retested at a later date to verify the initial result and then go from there.

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