Hello, welcome to the site! My name isXXXXX and I will try to assist you with your medical question, and any medical information you seek
I'm sorry to hear about this condition
Do you have any other tests like a C reactive protein?
Hello Dr Brims
I do not understand C Reactive protein.I have only had the following tests:
ANF screen - positive
RA IGM EIA - 0
Anticardiolipin IgG 2.8777
Anticardiolipin IgM 1.366
Anti DNA (ds DNA Abs) 4
CBC tests - all within normal range
Serum Complement C3 - 1.65
Serum Complement C4 - 0.71
C reactive protein - 4
Ah yes there it is!
It was within normal range
ESR - 23 (elevated)
Okay, there are still some other tests you should have to rule out lupus
Sorry continue if there are more tests
Are you there?
Lupus anti coag tests all within normal range
I have an underactive thyroid for which i have medication
thyroid function test normal
thats all the tests
any other tests?
Okay, I would advise you have anti Smith antibodies checked, which would be found in patients with lupus, and Anti-nRNP which may be found in lupus or mixed connective tissue disease
Either of the above conditions are still possible
Mixed connective tissue disease can also cause the symptoms you have
May I ask what is mixed tissue disease please?
I am here
It is an auto-immune disease that causes joint swelling and fatigue
It is similar to lupus but not as severe
Is there a cure?
Would this be the cause of the red rash on my face which occurred following exposure to the sun?
There is no cure, but it may be treated successfully and controlled
It could be the cause, but it could also still be lupus, the tests you have done do not rule out lupus
Ah right, so it is inconclusive until I have further tests done?
Yes, that is correct
You're quite welcome
If you still have questions on this topic please feel free to ask
What does positive ANF mean please?
Anti nuclear factor
It means you have antibodies in your cells attacking your own cells
and what causes this?
Also, can this lead to cancer?
The cause is unknown, but it does not lead to cancer
If I continue to exercise will this worsen my condition as joint pain is severe (especially in knees and ankles) when I exercise
It may worsen your condition, you should have it x rayed to determine how sever the joint damage is
If the damage in your joints is severe, you may have to limit exercise
Okay I will avoid exercise impacting my joints
That is reasonable
If the condition worsens, how likely is it I will end up in a wheelchair in say 20-30 years?
That is not possible for me to predict at this stage
Also, what can I do to stop the shooting pains in my body, I have taken painkillers which do do not work
I have pain even now in my legs
You may need stronger medication like celebrex or higher doses of ibuprofen
I have been taking 400mg (x2 tablets) a few times a day to no avail
I will ask for more medication from my GP
I see, then you may need a drug like celebrex or oxycodone
When I was 22 I was diagnosed with Rheumatoid arthritis, I am 26 now and RA came back as 0 in my blood test
does that mean the cause of my swollen knees is not RA?
sorry i am now 36*
It means it is not likely RA
Is RA a symptom of lupus or mixed connective tissue disease?
No, it is a different condition
It is also an auto-immune condition
Ah right okay
Well you have been most helpful, I will wait until I have had further tests done as recommended by you
If you have questions in the future, you may request me by starting the question with "Dr Brims"
Will do, thank you again, enjoy the rest of your evening.
If you have no other questions on this topic, you may click a rating button to exit the chat session
Fabulous, will do that now.