I am sorry that your question was not answered for quite long.
Seroquel is eliminated in about 42 hours from the body. So this duration would be crucial. But peak plasma levels are achieved at around 2 hours, so in about 6-12 hours, about half of the medication would be excreted from the body and dangers like heart blocks would be reduced. Please read this resource about the pharmacology of Seroquel;
Following are the answers of your questions;What are the chances subject can experience sudden organ failure (inc. kidney failure), fatal heart arrhythmia, short-term or long-term neurological deficits?
With the convulsions and coma; long term neurological deficits may occur. The exact chance of these complications in an individual cannot be ascertained; as there can be huge variations. But convulsions and coma are not good signs. With a good urine output and stable blood pressure; kidney failure would be not much likely. The major excretion of this drug is from liver and after 24-48 hours; the risk of liver failure too would decrease significantly. Since the pulse rate is good with no irregularity; chance of heart arrhythmia too would decrease in 48 hours.
Doctor on-call said watchful waiting only course for now, will take approximately 24-72 hours for all Seroquel to be "flushed out" of body.
Yes, Seroquel is likely to be eliminated in around 42-48 hours.Chances for awakening/becoming responsive to stimuli within next 24-28 hours?
With coma; chance of awakening in next 24 hours is quite low.
Outlook if not responsive within a 72-hour framework?
If the subject is unresponsive in 72 hours; outlook is not likely to be good and may point to brain insult.
Please read this reference resource;
Please feel free for your follow up questions.
I would be happy to assist you further, if you need any more information.
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