Hope the following points will clear the raise in your liver enzyme;
1) The liver function tests may be abnormal even in patients with a healthy liver.
2) Studies evaluating the clinical significance of these abnormalities have demonstrated that serious underlying liver disease is uncommon in many individuals.
3) Just this level of enzyme elevation is found in almost 10% of cases without any disease.
4) Only a persistent increase of two fold for three months will need further studies or invasive investigations like liver biopsy.
5) The other causes should be observed if there is no history of any medications, alcohol abuse and investigation for hepatitis B and C are normal and there are no medical evidence of the following diseases (which can elevate these enzymes); muscle disorders, thyroid disorders, celiac disease, and adrenal insufficiency).
Just this mild raise of ALT does not point to cirrhosis. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are intracellular liver enzymes with mitochondrial and cytoplasmic forms. Absolute levels of aminotransferases correlate poorly with the severity or extent of level damage and do not provide reliable prognostic information. In addition to hepatic injury, there are many other factors that may affect aminotransferase serum levels. Hyperthyroidism has been noted to raise both ALT and AST levels. Following causes should be considered in your case;
1) Non alcoholic fatty liver disease
2) Hepatitis A to E
3) Other virus; Epstein-Barr, cytomegalovirus, and HSV
In your case following approach would be done to control these raise of liver enzymes;
1) Weight reduction
2) Stopping alcohol if you do.
Further investigations required would be (if not done earlier or rise persists after 6 months);
1) serum protein electrophoresis for autoimmune hepatitis
2) thyroid-stimulating hormone levels;
3) creatine kinase levels;
4) antibodies for celiac sprue;
5) alpha-1-antitrypsin phenotype and levels;
6) adrenocortical insufficiency (Addison's disease)
If these investigation do not reveal anything abnormal; I would not be worried in your age group and only a 6 monthly or yearly check up of liver functions would be advised.
Please feel free for your follow up questions.
I would be happy to assist you further, if you need any more information.
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