is bowen's disease systematic, or can other lesions on the body simply be psoraisis?
Greetings.Bowen disease in majority of instances appear with a single lesion on the body. So your other lesions are not likely to be Bowen disease. Though a biopsy of the other lesion is mandatory to pin point the cause. This can be co-incidence of appearance of Bowen disease and other lesion like psoriasis simultaneously or just in small duration apart. Apart from psoriasis; other causes which mimic Bowen disease are actinic keratitis and lichen simplex chronicus.Please feel free for your follow up questions.
I would be happy to assist you further, if you need any more information.
I have found NIH results that told me that if I have Bowen's Disease confirmed, I could not have psoriasis at the same time...it would be more Bowen's manifesting in another part of the body that would look like psoriasis, but would by necessity be lumped in the the Bowen's Disease family.
You are very welcome, Gene.Not all of them have to be biopsied. Only 2-3 have to be biopsied, which will confirm the cause. Bowen disease may occur due to low body immunity or exposure to actinic rays of sun. Actinic keratitis also occurs due to sun; so other lesions may be related.Just an interesting study for your reference;Bowen's disease of the umbilicus simulating psoriasis vulgaris.Kolbusz RV, Fretzin DF.
Department of Pathology, Michael Reese Hospital & Medical Center, Chicago, Illinois 60616.
Bowen's disease and other primary cutaneous malignancies are uncommon in patients with psoriasis. Primary malignancies of the umbilicus are also unusual. Plaques of psoriasis and Bowen's disease may appear morphologically similar, requiring examination of a biopsy specimen for definitive diagnosis. We report on a patient with psoriasis who experienced Bowen's disease of the umbilicus that was initially believed to be psoriasis.
It is privilege assisting you.
Just an interesting reference for you, Gene.Proc R Soc Med. 1932 May; 25(7): 1033–1034. PMCID: PMC2183776Bowen's Disease with Prickle-celled Carcinoma and associated with PsoriasisW. N. Goldsmith Copyright and License information ►http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2183776/
Hello Dr. Arun,
Hello Gene,Your major concerns are;1) Are all the lesions Bowen disease? Biopsy of any of two would be able to confirm it. Not all of them have to be biopsied.2) If all are Bowen disease; you need the local treatment or systemic treatment (to eradicate it from the root)? It would need local treatment and systemic treatment would not be needed as it is not a systemic disease. The appearance of the lesions simultaneously is a co-incidence. Once the present lesions are treated, recurrence on the same sites or elsewhere on the body is not very likely.Bowen disease is caused by;1) Chronic UV radiation: chronic sun damage.2) Arsenic exposure3) Human papillomavirus (HPV)4) Genetic factors, 5) Other chemical carcinogens, 6) X-ray radiation.The most of causative affect the skin; so it would not be considered as systemic disease. It affects specific skin cell called keratinocytes. You perhaps are worried that if it keep on recurring in future, there are some inherent factors which are causing it. Most of the factors are skin related (except the genetic factor).This further recurrence can be prevented by;1) Increasing body resistance2) Using Sun screens3) Photoprotective clothes.
Hello again Dr. Arun,
You are very welcome, Gene.Your dermatologist should have taken a detailed history and also considered the biopsy for the confirmation of other lesions. Bowen and psoriasis have different modality of treatment. And Bowen which has multiple lesions is treated in same way as a solitary lesion.
Thank you very much Dr Arun!
I have the conversation going with my dermatoligist now!
I really appreciate your guidance on this and I will continue my follow up with my Primary Care Physician and my Dermatologist!
Bests to You!!!
You are very welcome, Gene.Thanks for your kind words.I would be grateful, if you rate our conversation as excellent.Thank you.My best wishes,Dr. Arun
I did click on 'EXCELLENT SERVICE' :)
It took me to a page saying I was not logged in, so please let me know if i need to contact Just Answer to tell them I was getting an error message.
Also, I wanted to give you a great response and tip, but it just took me to the error page.
Either way, I would love to recommend you to friends, is there a way for me to refer you on justanswer.com or another way to get your advise?
Thanks Gene, for all the time taken and your kind responses.Please contact the site administration, if you can. I am also informing them about the error message. Though the excellent service rating has been recorded. I appreciate it.This is my profile page link, where you and friends can ask me question directly, by posting question in the box. It gives me a lock of 15 minutes. http://www.justanswer.com/medical/expert-drarunphophalia/The other way to ask question is to start the question as, "For Dr. Arun only."Cheers,