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Valarie
Valarie, Nurse (RN)
Category: Health
Satisfied Customers: 1228
Experience:  36+ yrs exprience medical, surgical, wound/skin care, nutrition, geriatrics, rehab, management
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What can cause Warafin to not work at thinning blood

Resolved Question:

What can cause Warafin to not work at thinning blood?
Submitted: 5 years ago.
Category: Health
Expert:  Valarie replied 5 years ago.
Hello. Thank you for coming to JustAnswer with your question, and welcome. Vitamin K has an antagonistic effect to warfarin, and is found in many foods. Other possible sources are vitamin supplements. Foods include beef liver, broccoli, brussels sprouts, cabbage, collard greens, endive, kale, lettuce, mustard greens, parsley, soy beans, spinach, Swiss chard, turnip greens, watercress, and other green leafy vegetables,asparagus, avocados, dill pickles, green peas, green tea, canola oil, margarine, mayonnaise, olive oil, and soybean oil. Other possibilities as well: Snack foods containing the fat substitute olestra have added Vitamin K; cranberry juice and pomegranate juice can cause instability in your lab values (INR) that monitor warfarin; soy milk may also be antagonistic to warfarin. Here is a link that lists other possible interactions from herbal products and some medications: http://my.clevelandclinic.org/drugs/coumadin/hic_anticoagulant_medication_warfarin_coumadin.aspx
Customer: replied 5 years ago.
Outside of diet and supplements and other medications...........physiologically speaking .......is there a blood disease or other problem that can cause warafin resistance
Expert:  fernando cruzado replied 5 years ago.
Warfarin needed dose is very variable depending on each person. perhaps you need a higher dose. it does not mean there is a disease
Expert:  Valarie replied 5 years ago.
Hi,
there are some conditions that can cause warfarin to have a decreased response:
--edema,
--hereditary coumarin resistance,
--hyperlipidemia,
--hypothyroidism, or
--nephrotic syndrome

Of course, your doctor can compensate by monitoring your INR as frequently as you need, and adjust the dose accordingly. Some patients remain stable on one dose; some patients require frequent changes of medications.
Valarie, Nurse (RN)
Category: Health
Satisfied Customers: 1228
Experience: 36+ yrs exprience medical, surgical, wound/skin care, nutrition, geriatrics, rehab, management
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