Hello and thank you for your question,
I agree with Ms. Schuyler that retesting cholesterol in 2 weeks was rather soon and the numbers will not reflect much of a change. The fact that they went up is not unusual either because they do tend to fluctuate depending on the diet for 3 days prior to the blood test. To take a true cholesterol reading it is actually recommended to abstain from red meat for 3 days and to have a very light dinner before the blood test.
Gemfibrozil and Fenofibrate are both used to reduce the level of triglycerides (TG) on the cholesterol panel. I, personally, prefer to use Fenofibrate. It has less interaction with other medications and it is only once a day dosing. So I think that will be a good switch.
In terms of Avas and Ezitimibe. Avas, which is branded in United States as Atorvastatin (Lipitor), is a good medication. It lowers overall cholesterol and "Bad" (LDL) cholesterol. It also has properties of preventing heart attacks and strokes. Ezitimibe, although not harmful and is safe to take with other cholesterol lowering medications, has not shown any health benefit in many research studies.
So my suggestion would be to switch to Fenofibrate and add small dose of Avas and wait for at least 6-8 weeks before rechecking the cholesterol. For 3 days prior to recheck, your wife should avoid red meat and have a very light dinner the night before the blood test.
I hope you find this information helpful. Please feel free to follow-up with any other questions you may have.
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Best wishes and good luck,