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Hello and thank you for your question,
Could you please tell me how long you have had this problem for? If you take several days off from running, does the knee continue to feel unstable? Is there any pain besides going up or down the stairs?
Thank you for your reply.
I am sorry for not getting back to you sooner. I was already logged off when you replied.
The most likely cause of knee instability is an injury or tear to one of the ligaments which holds the knee together. If you are a frequent runner, you could have damaged a ligament due to constant use of the knee (we often see this type of injury in runners due to use of the joint in a repeated fashion).
You will need to see an orthopedic doctor and have MRI of the knee done (x-rays will only show bones and soft tissue, MRI will look at ligaments and muscles). Many ligament injuries are treated with ice, anti-inflammatory medications (Motrin, Advil, Aleve) and rest. Sometimes physical therapy may be needed and if the tear is severe, you might need arthroscopic surgery to repair it.
Until you see your doctor, I would suggest using a knee brace (to improve stability) and to ice the affected knee. Also I would suggest not running on it until further examination is done (to avoid further damage).
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Best wishes and good luck,