Hello. Thank you for coming to JustAnswer with your question, and welcome.
What type of muscles twitches are you having?
And why was the prednisone prescribed?
How much prednisone are you taking and how long have you been taking it?
The serious side effect of prednisone that involves muscles weakness, spasms, cramps and twitching have to do with loss of potassium. The reason it is serious is because it can also affect your heart muscles. And usually this is with high doses of prednisone (which you are not taking) and prolonged therapy.
Most likely your fasciculations are just that. Occasional muscle twitches are fairly common in almost everyone. You may just need to drink more water, drink some milk and/or eat more fruit.
You should be fine if you wait until your appointment to report this to your doctor. If, however, your symptoms become actual muscle spasms with cramping and/or muscle weakness, you should report this right away.
You're very welcome.
You may need some extra calcium also. This can also cause muscle twitches.
The signs of potassium depletion you need to watch for is noticeable muscle weakness and perhaps pain. You would be able to tell the difference.
Have a good weekend!