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Could you please tell me if you have any associated redness on your middle finger? Does it feel warm? Did you wake up with this pain or did it start in the mid-day?
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There are a couple of possibilities for your symptoms. One of the possibilities is that you have gout attacks. Gout is a type of arthritis which affects individual joints. Gout is known to affect a joint on a big toe but in reality, it can affect any joint. Usually, pain is severe with swelling and sometimes redness.
Treatment for gout is actually anti-inflammatories, such as Aleve or Advil, rather then Tylenol. Also ice would help.
Another possibility is rheumatoid arthritis which often presents itself with pain and swelling in different joints. This is less likely.
I would suggest that you take Advil or Aleve today but follow-up with your doctor for further evaluation and testing. You can have uric acid levels checked to look for gout and rheumatoid markers checked to rule out rheumatoid arthritis. I would also suggest that you get an x-ray of your fingers/hand.
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Do you have any other questions I can answer for you? Anything I can clarify?
Uric acid cannot be lowered immediately. There is a prescription medication which needs to be taken daily to lower uric acid levels (it is called Allopurinol). However, reducing uric acid levels is not necessary to treat an acute gout attack. The goal in treating acute gout attack is decreasing inflammation and swelling. For that, Ibuprofen (Advil) works great - each Advil pill 200 mg. You need to take 3 of them at a time, three times per day (always with food). Pain usually subsides within 24 hours. Tylenol is not an anti-inflammatory medication so it is not recommended in treating gout or any other acute arthritic conditions. Your doctor should check your uric acid levels (blood test) prior to giving you anything to reduce those levels.
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Lisinopril and Ibuprofen have no interactions and can safely be taken together.
Ibuprofen should be avoided if you have history of ulcers in your stomach but otherwise it is completely safe to use for 1-2 days. You do need to take it with food though (to avoid stomach irritation).