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Welcome to Just Answer and thanks for your question. The only time it is ever necessary or useful to clean a colon is when a medical procedure like a colonoscopy must be done. The cleansing products are nothing more than strong laxatives which are not healthy or necessary on a routine basis. The colon cleans itself in the normal course of digestion. Rushing food, medications, etc. through the digestive system interferes with proper absorption of regular medications as well as vitamins.