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Usually a skin or dermal test is done to test for the allergy, before injecting the restylane. Allergy to it is not common, and in substantial number of population results can be good.
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Distribution of the fat is very individual and depend on more on the genetic factors. If it is associated with the truncal obesity or abnormal weight distribution elsewhere in the body, hormonal assessment is usually done.
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An hormonal assessment would be prudent and before getting the injection, a skin sensitivity test for allergy is an essential precautionary measure.
Dr. Phophalia has provided you with excellent information on Restylane so I hope you will accept his answer. Restylane is for use in plumping up wrinkles such as those from the nose to the mouth (nasolabial folds). For flat cheeks you should contact your cosmetic surgeon since Restylane isn't used for this purpose. Implants may be a more permanent solution for you since Restylane needs to be injected every several months to maintain wrinkle reduction.