How JustAnswer Works:
  • Ask an Expert
    Experts are full of valuable knowledge and are ready to help with any question. Credentials confirmed by a Fortune 500 verification firm.
  • Get a Professional Answer
    Via email, text message, or notification as you wait on our site.
    Ask follow up questions if you need to.
  • 100% Satisfaction Guarantee
    Rate the answer you receive.
Ask Victoria Your Own Question
Victoria, Chiropractor
Category: Health
Satisfied Customers: 590
Experience:  25 years overall experience in health care from hospital-based intensive care to private practice
Type Your Health Question Here...
Victoria is online now
A new question is answered every 9 seconds

what does gliosis and astrocytes found on an MRI Brain mea

Resolved Question:

what does gliosis and astrocytes found on an MRI Brain mean?
Submitted: 7 years ago.
Category: Health
Expert:  Victoria replied 7 years ago.

When neurons in the brain are damaged, the astrocytes which are star-shaped cells that have a supportive neural function, rather than directly participating in sending or propagating neural messages/information, accumulate in the area of damage and proliferate forming a scar in the area of injury. It is the most important histological sign, signifying that an injury has indeed occurred. Gliosis is seen in association with neurodegenerative diseases such as Alzheimers, multiple sclerosis following an acute attak, Parkinson's, prion disease, etc. Demylination specifically refers to the white matter which respresents the myelin sheath which is a fatty covering that overlies and helps protect the nerve axons. Its integrity to critical to propagating the nerve impulse and when disrupted the signal gets disrupted such that the nerves are unable to adequately "talk" to the rest of the body. This is what occurs in MS or multiple sclerosis.
Ischemia is a lack of adequate blood flow to the tissues and if not reversed quickly, especially in the brain will lead to cellular injury and death. The astrocytes respond and accumulate and proliferate in the area of injury, forming a glial scar which may be seen on MRI. It is a nonspecific process in that responds to any type of neuronal damage or loss. After a stroke the neurons die and are replaced by gliosis. If unclear, feel free to ask further questions.

Hopefully you have found this information helpful. If so, please remember to click the green accept button so that I may get credit for my work. Your taking the time to leave positive feedback would also be greatly appreciated. Of course, bonuses are the ultimate reward and considered very special indeed! Thank you.

With warm regards,


Victoria and 4 other Health Specialists are ready to help you