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Dr. Mark
Dr. Mark, Doctor (MD)
Category: Health
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Experience:  U.S. Physician/Surgeon in Neurosurgery
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How long does flexeril stay active in your system I

Resolved Question:

How long does flexeril stay active in your system? I am 5''11" and about 195 pounds and have been taking this for two or three months (two or three a day) for a herniated disc.
Submitted: 8 years ago.
Category: Health
Expert:  Dr. Mark replied 8 years ago.
Flexeril has a relatively long half-life (the technical term for how long it takes to eliminate 50% of the drug from your body) at about 18 hours.

Therefore, the drug will stay active about 5 half lifes, or 5x18 hours, or 90 hours before nearly all of it is out of your symptoms.

In other words, if you stopped taking it today, it would be nearly 4 days (or a little bit longer) before the drug were "out of your system".
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