Yes this could be making a difference since there was no way your ankles could have come into contact with anything that could cause the breakout. While this could still be fungal it sounds more like a circulation issue and you might want to consider contacting your physician and letting them know what is going on. I would also recommend picking up a package of water pills from the drugstore to see if this does not seem to help with the swelling. In some cases when you have swelling it can also cause sweating so this could be a type of heat rash as well. I would continue with the Neosporin and elevate your feet as much as possible and see if this does not help but if they do swell more or if the rash does not go away within the next 48 hours it would be best to be seen by your physician.