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Vickie
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Experience:  7 years exp. on surgical floor, plus many other areas, Emergency Medical tech, 19 yrs total medical.
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Mirena

Customer Question

Is the progesterone hormone release in Mirena similar to the progesterone hormone in Depo Provera?
Submitted: 11 years ago.
Category: Health
Expert:  Kerry replied 11 years ago.

HiCustomer/P>

Depo Provera is a hormone injection that lasts for 3 months to prevent pregnancy. The injection contains synthetic progesterone and no estrogen.


http://www.fwhc.org/birth-control/bcdepo.htm


Mirena contains levonorgestrel, a hormone commonly used in birth control pills.


http://www.mirena-us.com/howmirenaworks.html


So yes, they are two different drugs.


Hope that helps,


Kerry

Customer: replied 11 years ago.
Reply to Kerry's Post: Kerry~
Thank you for your response. I am trying to determine what kind of progesterone is used in Depo Provera. Mirena does not include estorgen, like Depo Provera, but does it use the same kind of of progesterone (levonorgestal) as Depo Provera? I had a negative reaction to the Depo Provera and I want to see what my risk is of potentially having the same type of reaction with the Mirena.
Also, is the dosage the same for each or is Mirena a smaller dosage because of the IUS?
Thanks,
Emily
Expert:  Kerry replied 11 years ago.

Hi again


I'm sorry I couldn't answer your question better. Perhaps you could call your local pharmacy. A pharmacist should be able to answer your question.


Hope that helps!
Kerry


Expert:  Vickie replied 11 years ago.

Dear XXXXX,


Mirena only contains a low dose of the hormone levonorgesterol – a progesterone, therefore it can be used by women who have problems with estrogen. The Mirena is the current standard brand. FibroPlant is a unique "frameless" device is very small and secretes a very low dose of progestin. It appears to have very few hormonal effects, although comparison studies are needed to prove any significant advantages over the Mirena. The LNG-IUS releases progestin for up to seven years. Progestin released by an IUD mainly effects the uterus and cervix and so it causes fewer widespread side effects than the progestin pills do. (It should be noted that the other major IUD--the Copper T--may increase bleeding.) Depo-Provera uses a progestin called medroxyprogesterone. Unlike users of the implants, most users of Depo-Provera stop menstruating altogether after a year. It may be beneficial for women with heavy bleeding, severe cramps, or both. Women who eventually want to have children should be aware that Depo-Provera can cause persistent infertility for up to 22 months after the last injection, although the average is 10 months. Weight gain can be a problem, particularly in women who are already overweight. Of some concern was a 2002 study that found changes in the arteries of long-time users suggesting a risk for future heart disease. More research on this finding is warranted.


  • Progesterone is actually the name for the natural hormone.
  • Progestogen is a synthetic form.

  • Progestin is the term for any agent, natural or synthetic, that causes progesterone effects. It is used as the general term in this report.

  • I hope this has helped you out some, the two hormones are similar, only one is natural and one is synthetic. I am listing the website where I found this information for your reference...


    http://adam.about.com/reports/000100_7.htm


    Good Luck to you!

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