you'll need to have a long term status EU on basis of the respective directive (Art. 2 b) in order to transfer the title to another European country.
Usually, you'll obtain that title after being 5 years in the country and be able to maintain yourself and your family.
In Germany this title is also fixed in national law. In Italy it should not be any different.
Before that you'll need to have a blue card (highly qualified -> scientists, etc.).
Starting a business can be quite a hassle depending on the type of business (if special permits are required).
However, without a residence permit you will not be able to do so.
To obtain a permit just by opening a business, investing money and employing people requires a regional necessity for that business. Usually this does only match large investments.
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