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Welcome, I'm Chris (aka Moose), my normal schedule online is around lunch and after dinner past midnight.
What year model?
With coils 6 and 8 unplugged does it run the same?
Have you checked the signal from the PCM to the coils and injectors?
Have you done a compression test on these cylinders?
So if I understand correct your coils for 6 and 8 are getting power but no ground pulse?
No ground pulse means you have broken wires from the coils to the PCM or the PCM is bad. Since you have replaced the harness that means your loss of ground pulse to these 2 coils is going to be faulty coil drivers inside the PCM meaning PCM replacement and programming is needed.
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Most locksmiths can program keys to a vehicle though they can not update a PCM if your replacement is not to the same calibration as your original.
So your all set.
Hello again Chris here,