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what wire or connector are you speaking of? the coil or the injector? do you have a multi meter? do you have a noid light or test light?
We need to see if the circuit is working. Disable the fuel pump or disconnect the inertia switch. Hook up a test light or noid light to the coil connector, crank the engine. You should see the light blink. You said we have power, you can verify 12 volts . If no flash from the coil connector we need to disconnect the connector to the coil and the PCM connector and ohm out the PK/LB wire. we have an open, high resistance or the PCM driver is bad. We should see less than 5 ohms
let me know if this truck ran with this misfire for a long time and if the codes were cleared and KAM reset after the coil was replaced
let me know what you find
when checking the coil circuit from the connector to the PCM the battery should be disconnected. If the meter reads OL we have an open. we are checking the ground side of the coil circuit.