Hello, I am John, a Ford dealer technician.
I hope I can help solve your problem quickly and accruately.
sounds like you either have sticking latches or seized door lock actuators. Best way to get this fixed is to take to a body shop. Body techs have alot of experience with these problems. First a tech will need to remove the door panels and then they will have to try to manually release the latch. Once that is done the problem can be found.
I hope this answer has been helpful to you! If you have any further questions please feel free to ask.
If this answer has been helpful please accept so I can recieve payment.