Is this your primary residence? (lived in the house for 24 months in the last 5 yr period)?
Ten up to 250,000 is excluded (for those filing as single) and 500,000 of gains for those filing Jointly
Here's the IRS guidance on this: http://www.irs.gov/publications/p523/ar02.html#en_US_2012_publink1000200711
Here's an excellent list, form Nolo.com
and here are some of the not neccessarily required things that MAY come to play
you're very welcome
the links here will stay active, if you'd like to come back for future reference
If this HAS helped, I would appreciate a feedback rating of 3 (OK) or better … That's the only way they will pay us here.
HOWEVER, if you need more on this, PLEASE COME BACK here, so you won't be charged for another question