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In proving that a grantor did not have the mental capacity to change the will or named power of attorney, this requires a significantly high burden of proof. Just because he died of Alzheimer's you have to prove by medical evidence that he did not have the mental competency at the time he granted the PoA or changed the will. This means medical evidence and witnesses as well. These cases are not simple and mandate you have an attorney representing you. The case is going to hinge solely on the evidence you can present that at the time he made these changes he was not competent. If you are able to meet that burden of proof you can get the original will reinstated and enforced by the court.
However, as a surviving spouse, she is still going to be entitled to her spousal share of the estate, which is 1/2 of everything acquired when they were married and 1/2 of all remaining property. So she is still entitled to a share of the estate.