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Hi. I'm online and happy to answer your question today.
That is a very good question.
Fortunately, there is no significant risk of germs on your eyeglasses moving into your eyes. This is especially true in a normal, healthy eyeball.
Concerning vapors from soap wafting up and irritating your eyes, I guess it would be possible for your eyes to be irritated by the soap if you were highly allergic to that particular soap. If this were true, however, I would expect you to have a significant allergic reaction the soap everywhere it touches your body.
Also, soap has a very low vapor point so I do not think there is much in the way of "fumes" that come off of it.......
So, to answer your question directly, I very much doubt that these two issues would be the source of any eye irritation you might be experiencing.
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Does natural-based dish detergent also have a low vapor point too? (as far as vapors and stuff getting into the eyes?) What if a small amount of natural dish detergent or laundry detergent is in your hair.