As you probably already know a roth spot is a distinct area of retinal hemorrhage that has a white center. There are many things that can cause the white center. It can be from a collection of white blood cells, fibrin (clot material), Platelets or it can just be an artifact from how the light is being reflected off your retina in the area of the retinal bleeding.
While it is true that roth spots can be seen in leukemia and diabetes (as you have already stated) they are also present in a number of other disease processes such as pernicious anemia, sickle cell disease, scurvy (very rare on a normal diet), and collagen vascular diseases such as systemic lupus.
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Since you do not have any findings to suggest leukemia or diabetes I would look for one other condition where I have seen roth spots in my practice: subacute bacterial endocarditis causing focal septic chorioretinitis secondary to emboli. I would recommend a echo cardiogram and, possibly, a consultation with a cardiologist.
Yes. It is possible to have a roth spot with nothing serious being wrong. That being said it is important to rule out diseases known to be associated with this retinal finding before reaching that conclusion.
One other thing to keep in mind is the expertise of the doctor who diagnosed you with a roth spot. Make sure she is an ophthalmologist
or a retina specialist as less trained individuals may mistake other retinal findings for a roth spots.
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