Hello and thanks for your question. I am an ophthalmologist and treat these chalazia on a daily basis. I would be happy to help you with your concerns.
For persons such as yourself who get these recurrent chalazia, it is often accompanied by an eyelid inflammation called blepharitis. The inflammation in the eyelid from blepharitis causes poor functioning oil glands and can predispose to chalazia. In order to treat blepharitis, everyday in the morning you should do two things: 1. hot compresses and 2. eyelid scrubs. You should do hot compresses for 5-10 minutes over each eye at the same time. It should be as hot as you can tolerate without burning your skin, massaging the eyelids while they are on there. Then, use either commercially available preparations or a dilute baby shampoo solution to scrub your eyelashes on all 4 eyelids. The commercially available preparations are called Ocusoft or Sterilid which are both over-the-counter eyelash scrubbing treatments. These cost more money but are quicker to use. Otherwise, the cheaper alternative is the dilute baby shampoo (4-5 drops Johnson's shampoo in 1/4 cup warm water), you will take the wipe (or dip a qtip in the dilute baby shampoo solution) and use that to scrub right on the eyelashes of each eyelid for 15 seconds. That will take 60 seconds when done to all 4 eyelids. The scrubbing is done right on the eyelid margin, where the eyelashes come out. After that, just splash some water on the eyes and you're done.
It does take about 3-4 weeks of doing this consistently every day before it really kicks in, so don't stop it thinking it's not working.
For anyone with recurrent chalazia, these treatments are a necessary baseline. I also recommend for my patients to use the doxycycline as little as possible to help keep them away, but some people such as yourself need it more than others. You may consider trying doxycycline 20mg twice daily. The brand name for this concentration is called Periostat (used in dental procedures). At this lower dosage you still get the effects on the oil glands, but less of the bacterial killing properties that may lead to bacterial resistance.
Lastly, taking a daily omega-three fatty acid supplement can also help thin the oil secretions which can help decrease the incidence of these chalazia.
You may be someone with such active problems with this that a nightly or every other nightly steroid/antibiotic dose put into the eye (drop or ointment form) may be necessary as well.
Does this information help address your concerns? Does this make sense? Do you have any other concerns that I haven't addressed?
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My opinion is solely informative and does not constitute a formal medical opinion or recommendation. For a formal medical opinion and/or recommendation you must see an eye doctor.