Dry eye syndrome has been found to be associated with collagen vascular diseases like lupus, rheumatoid arthritis etc. Treatment is often difficult and I can see that you have already had been given some of the best options available. To understand your condition better and discuss it with your ophthalmologist, you can follow this link - http://www.emedicinehealth.com/dry_eye_syndrome/page2_em.htm. The management of your problems will involve ophthamologist, dermatologist and and a rheumatologist/orthopedic surgeon. Thanks.