Avastin is not cortisone or indomethacin. Avastin is a brand name containing the drug bevacizumab which is an anti-VEGF(anti- Vascular Endothelial Growth Factor). It can be given to treat macular edema
. Research implicates VEGF as an important mediator of vascular permeability and CME. Therefore, clinical trials are being conducted to evaluate the benefit of VEGF inhibitors in treating CME associated with different conditions, such as diabetic macular edema and retinal vein occlusions.
Injections of long-acting depot steroids like corticosteroids into the sub-Tenon space usually are more effective and commonly are used in the treatment of noninfectious uveitis
but they have side effects like galucoma. Peribulbar injections have a greater risk of intraocular
injection than a subconjunctival approach; however, the drug delivery to the retina is superior when administered into the posterior sub-Tenon space.
acetonide has been found to effectively reverse CME in eyes with many conditions, including pseudophakic CME, retinal vein occlusions, diabetic macular edema, uveitis, and juxtafoveal telangiectasis. Clinical trials are being done to study the long-term benefit and safety of this treatment approach.
When CME is associated with diabetic macular edema, focal laser photocoagulation according to the guidelines of the Early Treatment of Diabetic Retinopathy
Study (ETDRS) should be followed.
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