Hi there and welcome
You can, and it will not effect the computer as they will then run when you need them to run.
I advise you though to leave the Anti Virus software running though.
To disable the programs, press CTRL + ALT + Del and click on Task Manager
Then on Startup and you can disable them there
You can also right click on them in the startup folder and select delete for ones you do not see there
If you have any problems, or would like any additional information or assistance, please do not hesitate to let me know.
Else if you can take a second to rate my service by clicking one of the stars at the top of the screen then submit, that would be greatly appreciated.