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A 'no signal' and 'lost connection' indication may mean that some motorized appliance was On, and flooding the area with radio noise, blocking the wireless signal (if your monitor is a wireless-link type. If it was a wired type, that's a different sort of problem, and might be owing to a loose jack on a cable, a defective cable e.g. one that has been stressed at some point or points, or just not-quite-plugged-in at one end of the cable or the other, plus other possible problems.
Or the 'no signal' and 'lost connection' could simply mean that components in the wireless link are becoming defective.
Was the monitor reset recently, or was there a power failure recently?
Has it had this problem before?
What maker and model number is ***** nursery monitor please?
How old is the nursery monitor in question?