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Family Physician
Family Physician, Board Certified MRO
Category: Drug Testing
Satisfied Customers: 12816
Experience:  Medical Review Officer - Physician Trained and certified in drug test interpretation
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Would a single dose of Xanax 0.25mg show up on a urine drug

Customer Question

Would a single dose of Xanax 0.25mg show up on a urine drug screen? My daughter takes Xanax as prescribed--twice a day s needed--yet her drug screen 2 days later was negative for benzodiazepines, and she was kicked out of her doctor's practice. He said she must be selling it, which she is not doing. Thank you
Submitted: 5 years ago.
Category: Drug Testing
Expert:  Family Physician replied 5 years ago.
The simple answer to your question is YES, a single dose of Xanax can be detected in urine for several days.

HOWEVER, the answer isn't that simple; Many of the tests for benzodiazepines are not as sensitive at identifying alprazolam (Xanax) as they are for Valium. There are a number of reasons for "false negative" drug tests. This article describes many of those reasons including dilute urine, interference from other medications, and sensitivity of the test.
http://www.annclinlabsci.org/cgi/reprint/37/4/301

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