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Dr. Drew
Dr. Drew, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 16846
Experience:  Small Animal Medicine and Surgery
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I came home from work and my two dogs got into the heart

Customer Question

I came home from work and my two dogs got into the heart guard plus package and ate 24 doses
JA: I'm sorry to hear that. The Veterinarian will know if the dog will be able to digest that. What is the dog's name and age?
Customer: Baxter 2. Kodi 4
JA: Is there anything else the Veterinarian should be aware of about Baxter?
Customer: No besides over weight he is healthy
Submitted: 4 months ago.
Category: Dog Veterinary
Expert:  Dr. Drew replied 4 months ago.

Hi, thanks for your question today. Can you tell me what the weights of the 2 dogs are?

Customer: replied 4 months ago.
Baxter is 19 pounds, Kodi is 10
Expert:  Dr. Drew replied 4 months ago.

OK, thanks -- so was this the up-to-25 lbs size of Heartgard Plus? Do you know which of the dogs ate it all? Or was it likely to be both of them together?

Customer: replied 4 months ago.
up to 25 pounds, no clue which one ate, but 24 doses are gone
Customer: replied 4 months ago.
I am pretty sure it was a team effort
Expert:  Dr. Drew replied 4 months ago.

OK, let me do a worst-case scenario by assuming Kodi ate all 24 doses, since that would be the highest risk situation. I'll be right back.

Expert:  Dr. Drew replied 4 months ago.

OK, so here's what we've got. Each chewable tablet contains 68 mcg of Ivermectin (the active ingredient that is most likely to be a toxic risk in dogs). 68 x 24 tablets = a total amount of 1632 mcg of ivermectin. If Kodi ate all of that, it would be a dose of approximately 360 mcg per kg of body weight, assuming 10 lbs is an accurate weight. This is not automatically a life threatening dose of this drug, unless either dog is genetically at-risk for having difficulty with metabolizing this particular medicine. There is a gene mutation that affects certain dogs, which causes them to be at higher risk of side effects from Ivermectin. Most often, Collies, Border Collies, Australian Shepherds, and other breeds can be affected, but the gene can appear in any breed. Typically, side effects include lethargy, confusion, weakness, paralysis, unconsciousness, or seizures, and these effects can be quite serious. Effects would be expected to occur within about 4 to 6 hours after ingestion of the medicine, though often it's faster than that.

Expert:  Dr. Drew replied 4 months ago.

If more than 6 hours has passed, with no symptoms, then I would not have much reason to worry.

Customer: replied 4 months ago.
I work 12 hr shift and have no clu what time they got into the stuff, they are acting normal eating dood food now no vomitinh or issues noted at this time
Expert:  Dr. Drew replied 4 months ago.

Well, given that, it is likely that no issues will arise, unless it was within the last few hours that they got into the meds. There is the option of inducing vomiting, but this is not of much benefit beyond 2-3 hours after ingestion. I suspect that it's not likely to be necessary based on what you've described to me here.

Customer: replied 4 months ago.
24 doseswillbe ok it they remain symphone free for 6 hrs?
Expert:  Dr. Drew replied 4 months ago.

Based on my calculations, most 10-lb dogs would not experience life threatening toxic effects from eating all 24 doses. If we assume it was a shared effort, and both dogs ate some, the risk is even less.

Expert:  Dr. Drew replied 4 months ago.

Certainly if 4 to 6 hours passes with no neurologic symptoms like I described earlier, I would not see much reason to worry further, other than the usual caution to watch for digestive upset that could occur after eating *anything* unusual.

Customer: replied 4 months ago.
what would I be looking out for
Expert:  Dr. Drew replied 4 months ago.

Typically, side effects include lethargy, confusion, weakness, paralysis, unconsciousness, or seizures, and these effects can be quite serious. Effects would be expected to occur within about 4 to 6 hours after ingestion of the medicin

Customer: replied 4 months ago.
Ok thanks.. I will watch my boys for signs of weakness lethargy,weakness,papaylisand uncouscious BD and seizures
Expert:  Dr. Drew replied 4 months ago.

Watch closely, and get them to a veterinary emergency clinic if those signs appear. Merry Christmas!

Customer: replied 4 months ago.
Ok thanks
Expert:  Dr. Drew replied 4 months ago.

Just following up to see if everything is going well!

Customer: replied 4 months ago.
They seem fine.tolerate water no sign of vomiting.thankyou
Expert:  Dr. Drew replied 4 months ago.

Glad to hear it. Please let me know if you have any other concerns about this issue.

Expert:  Dr. Drew replied 4 months ago.
Hi,

I'm just following up on our conversation about your pet. How is everything going?

Dr. Drew