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Thank you for using Just Answer. My name is Rebecca; I am a veterinarian. Please give me a moment to type my answer.
I am sorry to hear you are worried about Lola.
Often when a dog suddenly does not want to go up stairs, it is due to back pain.
It could be a pinched nerve, or an inflamed disc. How much prednisone is she taking? If anything, prednisone can help with inflamed joints.
Having her checked out might be a good idea, and an Xray might also be a good thing to have if the examining veterinarian recommends it.
That is OK: I thought she was taking pills. Eye drops would not get much prednisone into her blood stream or body. She may need anti inflammatory and pain meds. The safest would be to get them from your veterinarian.
If she is not going up stairs she is telling us she is hurting, and her back is the most likely place. She would probably feel better with some pain or anti inflammatory medication, especially if this continues.
I hope you saw my response; I have not heard back from you. How is she doing? Was my answer helpful; can I answer anything else?