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Hi I'm Dr.Carole and I'm a small animal veterinarian. To answer your question yes it is safe to give Famotidine and I recommend it regularly. However, it might be worth some investigation as to why your dog is regurgitating. Has the vet done any bloodwork or x rays? When he brings up his food does he actively retch before hand or just passively bring it up without active abdominal contractions?