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I am sorry to hear you are worried about Billy.
This is probably a UTI (urinary tract infection) or possibly she has bladder stones. She is probably uncomfortable, so the sooner she is diagnosed and treated the better, but if she is eating and drinking, it could wait until tomorrow with your regular vet.
Yes, take a sample of urine when you see your vet.
Until you can take her in, giving supplements containing cranberry, or getting her to drink cranberry juice might help her feel better.
If she is straining and unable to pass urine, or if she stops eating, then she should go to emergency today.
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