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Hi this is Dr. Hill. She needs to be seen by a veterinary internal medicine specialist. I am so sorry she is that ill.
With that kind of history, I unfortunately would be looking for cancer. Unexplained weight loss, a negative exploratory surgery. During surgery, I hope they took biopsies of her intestinal tract. Whenever an animal has surgery for vomiting and no foreign objects or areas of concern are noted, it is standard of care to biopsy the stomach, two areas of intestines and lymph nodes. Many times cancer is there but not as a distinct mass.
Where are you in the USA? Lyme does not cause wasting like that unless they develop Lyme nephritis typically. Cancer is not as common in younger dogs but it definitely happens. Which wbc was elevated and how high were her counts. Putting a feeding tube in may significantly help her while you are trying to find out what is she has.
Shot in the dark, but severe allergies. Has anyone tried a steroid and a prescription hypoallergenic diet. Inflammatory bowel disease can get this severe
the gold standard test is biopsies. It is really too bad they chose not to do them. Dogs can get leptospirosis from standing water, but that does not fit here. They can get heart worm from mosquitoes but also does not fit. Why not go with the feeding tube, hypoallergenic diet and talk to them about steroids. She may have a turn around.
Not really, unless they are huge and could be isolated with an ultrasound.
More likely severe inflammatory bowel disease. See if they will do a treatment trial.
yes and diet change