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Hi there. My name is***** to hear that your Guinness is unwell. I will do my best to help with your question. First I have a few questions to help me better understand your situation.
1) What dose of prednisolone and what dose of azathioprine is he on?
2) Was it two weeks ago that the prednisolone was started, and one week ago the azathioprine started?
3) Are you able to check his gum colour, and the colour of the outer 'whites' of his eyes (or take a photo of each)?
There may be a potential drug effect relating to the azathiaprine itself, or a drug-interaction between the two drugs. This can involve toxicity of the liver, the gastrointestinal tract or the bone marrow. But it could also be the haemolyic anaemia itself that is the cause of his weakness.
That's good to hear he ate well. And it's promising that his gums and eyes are looking normal. I would have expected you to see some yellowness (jaundice) at either site, if it was liver toxicity, and paleness +/- jaundice if it was the haemolytic anaemia causing the problem.