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Dr. Gary
Dr. Gary, Dog Veterinarian
Category: Dog Veterinary
Satisfied Customers: 19580
Experience:  DVM, Emergency Veterinarian, BS (Physiology)
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I have a 14year large male lab. He eats well and has always

Customer Question

I have a 14year large male lab. He eats well and has always been healthy. He has maintained his weight of 84 pounds.Within the last 3 months his muscle mass has lessoned, including around his cranium. rear legs are a littlle weaker. Yesterday a piece of hair fell out of his neck leaving a two inch bald spot without rash, bite or irritation... just smooth white skin. i have had his blood tested and his liver enzymes were elevated; ALT 140 then amonth later 262, ALP 961, then 1177. ASt was normal . all other blood results also normal except for elevated cholesterol, (437). What do you think may be the cause? ***@******.***
Submitted: 10 months ago.
Category: Dog Veterinary
Expert:  Dr. Gary replied 10 months ago.
Hello. Thanks for the question. It sounds like there is probably some type of chronic liver disease present. That could be cirrhosis, chronic active hepatitis (an auto-immune condition), liver cancer or even something like Cushing's disease. If you want answers, the next step is ultrasound and biopsy of the liver. That should give you a definitive diagnosis. From there, you treat with either antibiotics or steroids or surgery or chemotherapy based on what you find. If nothing else, I would put him on a liver supplement of Denosyl (SAMe). I would give 425 mg once daily. I hope this helps, let me know if you have any other questions.
Expert:  Dr. Gary replied 10 months ago.
Hi Grant,

I'm just following up on our conversation about Jack. How is everything going?

Dr. Gary