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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 23776
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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My 25 pound dog ingested 80mg Clomicalm meant dog,

Customer Question

My 25 pound dog ingested 80mg Clomicalm meant for another dog, what do I do?
Submitted: 6 months ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 6 months ago.
Clomipramine has a narrow margin of safety. Clinical signs can be seen at or slightly above therapeutic range - at 1-1.5 mg/lb or 25 - 37.5 mg in Lilly. It would be prudent to induce emesis by administering 2 measuring tablespoons (30 mL) of 3% hydrogen peroxide by means of a small poultry baster placed between Lilly's cheek teeth and cheek. Lilly should vomit within 15 minutes. If not, please repeat the same dose.
Expert:  Dr. Michael Salkin replied 6 months ago.
Overdosage with tricyclics such as clomipramine can be life-threatening (arrhythmias/irregular heart rates, seizures, cardiorespiratory collapse). In dogs, lethal doses are approximately between 23 - 46 mg/lb, however. Inducing emesis is predicated upon Lilly ingesting the 80 mg within 2 hours.

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