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HI this is DRB and I would be happy to help you with this. Edema in the back legs of a 13 year old Golden Retriever is never good.This is almost always an indication of a cancer....usually a lymphoma......and I am very sorry to have to relay this type of information to you. Anti-inflammatory might make your dog more comfortable but will not get rid of the edema.
If it is possible for your pet's sake I would try to have him seen as soon as you can. I am online so let me know if you have additional questions.
I am standing by for questions....
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Please let me know if you need additional assistance. I check my computer every night and will be happy to answer any follow up questions.
Please hit rate my service as that is the only way I am compensated. A positive rating will not close our conversation as I am happy to answer follow up questions. Thank you very much! DRB