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Hi there, I'm Dr. Sara. I'm a licensed veterinarian who works exclusively with dogs and cats. I'm sorry to hear that your pup is acting oddly - how long has this been going on? When did she last eat?
Being unresponsive is one of a short list of problems that I'd typically recommend an emergency room visit to have evaluated. Twitching is a really difficult symptom to evaluate without being able to actually see your pet in person. It could be something pain related, it could be a neurologic symp***** *****ke a partial seizure, it can be anxiety (which looks more like shivering), it could be a sign of a toxin ingestion - the list is really long. What's she up to now?