I do appreciate you are not sure, but in a case where we re not we have to err on the side of caution with out small pups.
With that in mind, the Prion is a lesser issue in this case as its main side effects are restlessness, aggressiveness, and elevation of the blood pressure. And we'd likely have had a hint of these if she had this that long ago.
Otherwise, the reason I asked about the Rimadyl's strength is because there is a dosing range and not one set dose for a Labs. Therefore, if she gets one tablet twice daily, I can only assume she has been getting 100mg tablets. And if that is something your pup could have gotten, then that is a problem. While its not a dose that is likely to damage the pup's kidneys, it certainly cause GI upset and even more worrying a stomach ulcer. And I have to note that we may not see signs of the latter for a good 24 hours. So, we need to tread with care.
In regards ***** ***** to watch for, we'd have to be monitoring for appetite loss, vomiting, diarrhea, belly pain, paling of the gums or black stools. Any of those signs would tell us that the gut is at least irritating but may be becoming damaged.
Now since it has already been over an hour, we are past a point where we could induce vomiting to get the tablets back. Therefore, our main protective step here would be to use activated charcoal at this stage. This is available over the counter from the pharmacy (ask for the high strength version in grams, not the one for gas since you will need a lot of these) and works by binding any remaining material in the stomach. For activated charcoal, we tend to give 1-4 grams per pound every 8 hrs. This can be mixed with food to be fed or with water to syringe feed (do note that it stains, so keep it away from white carpets/clothes). This will just limit how much is absorbed and reduce the intoxication risk here. And be aware if you use this, it will cause black stool itself but obviously we'd expect it with that.
Finally, since gut damage is a worry, we'd want to consider having this pup on gastroprotectants from her vet. Though in the meantime, you can start an OTC antacid like Pepcid (More Info/Dose @ http://www.petplace.com/article/drug-library/library/over-the-counter/famotidine-pepcid) or Zantac (More Info/Dose @ http://www.petplace.com/article/drug-library/library/over-the-counter/ranitidine-hcl-zantac) to reduce stomach acid pH and thus risk of ulcers. These are usually given 20 minutes before offering food to allow absorption and of course you want to double check with your vet before use if your wee one has any know health issues or is on any medications you haven't mentioned.
Afterwards, we'd want to feed small frequent meals of a light diet option for a few days. Examples of an easily digestible diet include cooked white rice with boiled chicken, boiled white fish, scrambled egg, or meat baby food (as long as its free from garlic or onion powder). Ideally, we want to offer this as small frequent meals to give the acid something else to chew on besides the pups stomach wall.
Overall, if we aren't sure if the pup had the tablets, then we need to err on the side of caution. therefore, we'd want to use the above now while monitoring closely for those signs I noted. If the pup remains stable we are happy, but any of those signs and we'd want it seen urgently to offset this risk here.
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Please take care,
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