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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 24377
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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I gave my dog who weighs 20-22 lbs. the medication.

Customer Question

I gave my dog who weighs 20-22 lbs. the medication. promethazine 25 mg. how dangerous is this. It was a mistake, is there something I can do?
Submitted: 9 months ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 9 months ago.

I might dose a dog with up to 0.23 mg/lb of promethazine as an antiemetic. A 22 lb dog, then might receive 5 mg. The bioavailability of this drug is very low (~10%), however, and so the most I'd expect 25 mg to do is cause transient dry mouth and sedation. To be prudent, you should induce emesis by dosing your dog with 20 mL (one measuring tablespoon + one measuring teaspoon) of 3% hydrogen peroxide given with a small poultry baster placed between your dog's cheek teeth and cheek. Your dog should vomit within 15 minutes. If not, repeat the same dose.

Please keep me posted.