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Ask Dr. Michael Salkin Your Own Question
Dr. Michael Salkin
Dr. Michael Salkin, Veterinarian
Category: Dog Veterinary
Satisfied Customers: 24404
Experience:  University of California at Davis graduate veterinarian with 44 years of experience
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I am trying to figure out if this is a genetic disorder. I

Customer Question

I am trying to figure out if this is a genetic disorder. I own the sire of this 12 month old dog. Although I have had all of the recommended health testing, I want to be sure this isn't genetic.
The final diagnosis was: Concern for chronic rickettsial disease with secondary ITP
Submitted: 10 months ago.
Category: Dog Veterinary
Expert:  Dr. Michael Salkin replied 10 months ago.

You've described a pancytopenia which describes both decreased white and red blood cell lines. That's not consistent with an anticoagulant rodenticide but could occur with immune-mediated processes. Other possible causes include drug toxicities, Ehrlichia canis (a rickettsial disease) and parvovirus infection. We don't consider pancytopenias to have a genetic basis but I can't rule out a rare genetic disorder that might predispose to bone marrow necrosis and myelofibrosis - the replacement of hemic tissue by fiborus conmnective tissue, collagen, or reticulin fibers.

My condolences for your loss of your poodle. Please respond with further questions or concerns if you wish. I have to leave my computer for a few hours but I promise to reply as soon as I return if need be.

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