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Hello, this is Dr. Jess. I am sorry to hear about your dog. Is there any way to take a photo of her eyes? Is she having discharge from them? Rubbing or blinking excessively?
If you can take a photo, that may help. You can attach it using the "add files" link next to your send button. Is the discharge yellow or green or clear? What part of the eye or lid exactly looks swollen?
Oh my! That looks quite unpleasant for her! This isn't just a simple case of conjunctivitis, she has what is called chemosis, which is a swelling of all the conjunctival tissue.
Has she had any bloodwork done recently? Sometimes this can be the result of low protein levels in the blood (which may happen in end stages of cancer).
Ok. So this could be related to that, or could be a manifestation of her lymphoma. I know you said she is on prednisone orally, but topical steroids may be of benefit as well, and topical antibiotics may help if she has developed a secondary infection. The issue is if the underlying cause is something we aren't going to be able to fix, we may not be able to get rid of the chemosis, or we may improve it temporarily only to have it return...
I think it would be worth a try with topical steroids and antibiotics just in case if she is doing well at home right now otherwise. What do you have to lose by trying, you know?
Poor thing! Do you know if the neopolybac had hydrocortisone (HC) in it?
Ok. There are other topical antibiotics available for the eye, but I don't know if that is really the issue here. Honestly, I think given the severity of her eyes, it is out of my realm of expertise, and I don't know how much more info I can provide for you. I am going to open your question back up in case there is someone out there with more ophtho experience than myself!